mProX™ Human MARK1 Stable Cell Line

[CAT#: S01YF-1123-KX299]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1209	Magic™ Human MARK1 in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

MARK1

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Pigmentation Research; Reproductive Research

Related Diseases

Peutz-Jeghers Syndrome and Autism. Among its related pathways are Complement cascade and Glucose / Energy Metabolism

Gene ID

4139

UniProt ID

Q9P0L2

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

MARK1 and MARK2 are the most prevalent MARK kinase family members in the heart among MARK1, 2, 3, and 4. The identical HDAC5 sites that PKD targets are phosphorylated by MARK2, and these sites are shared by all other class II HDACs. In addition to its ability to phosphorylate HDAC7, MARK3 seems to phosphorylate the amino-terminal 14-3-3-binding site more frequently. In cardiomyocytes, MARK kinases do not appear to mediate HDAC phosphorylation and export, despite these findings. Therefore, more research is required to ascertain whether MARK kinases are involved in the remodeling or development of the heart. The customized MARK1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Laura

We received the MARK1 KO cell line in perfect condition. Feb 20 2020

chat Verified Customer

chat Michelle

The MARK1 cell line surpassed my expectations in terms of sensitivity and ease of use. Apr 08 2022

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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