mProX™ Human MAPKAPK2 Stable Cell Line
[CAT#: S01YF-1123-KX296]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
MAPKAPK2
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
HeLa; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Inflammation Research; Digestive and Renal Research; Cancer Research
Related Diseases
Monocytic Leukemia and Inflammatory Bowel Disease. Among its related pathways are MyD88 dependent cascade initiated on endosome and Fatty acid metabolism
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The human MAPKAPK2 gene encodes the enzyme MAP kinase-activated protein kinase 2. A member of the Ser/Thr protein kinase family is encoded by this gene. p38 MAP kinase directly phosphorylates this kinase to control it. This kinase is known to work in concert with p38 MAP kinase to facilitate a variety of cellular activities, including as nuclear export, the regulation of gene expression, stress and inflammatory responses, and cell proliferation. It was discovered that its primary direct substrate in vivo is the heat shock protein HSP27. For this gene, two transcript variants encoding two distinct isoforms have been discovered. The customized MAPKAPK2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
David
For MAPKAPK2 drug discovery, this is a good choice.
Apr 15 2022
Verified Customer
Deborah
The cell line is ideal for helping to detect MAPKAPK2.
Jan 30 2020
Verified Customer
FAQ
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