mProX™ Human MAPK11 Stable Cell Line

[CAT#: S01YF-1023-PY36]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1222-KX411	Magic™ Human p38β(MAPK11) in Vitro Assay	Human		Kinase Assay

Product Information

Target Family

Kinases/Enzyme

Target Protein Species

Human

Host Cell Type

HEK293;CHO-K1;A549;HCT116;MCF-7

Target Classification

Kinase Cell Lines

Target Research Area

CNS Research;Infectious Research

Related Diseases

Syphilitic Meningitis; Disorder Of Sexual Development

Gene ID

Human:5600

UniProt ID

Human:Q15759

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

MAPK11 has been investigated in the context of cancer research, specifically in colorectal cancer cells and breast cancer cells. In the study on colorectal cancer cells, red kale extract was found to induce apoptosis in HT-29 cells through the caspase-dependent pathway, with significant upregulation of MAPK11 gene expression. In the study on breast cancer cells, transcriptome analysis and molecular docking predicted MAPK11 as a potential therapeutic target of curcumin, a natural compound with anti-cancer properties. Additionally, the study highlighted MAPK11 as a potential prognostic marker and therapeutic target for triple-negative breast cancer. Further research is needed to explore the specific role of MAPK11 in these cancer contexts.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Jordan Davis (Verified Customer)

How does MAPK11 influence lipogenesis and gluconeogenesis in the liver? Jul 28 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

MAPK11 plays a role in repressing lipogenesis and gluconeogenesis in the liver, as evidenced by studies showing that targeting MAPK11 can enhance lipolysis and glucose utilization. Jul 28 2022

chat Casey Brown (Verified Customer)

What is the role of MAPK11 in cellular stress response? Jul 06 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

MAPK11 is involved in the cellular stress response, particularly in inhibiting endocytic recycling of multiple cargoes under various extracellular stimuli. Jul 06 2021

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