mProX™ Human MAP3K2 Stable Cell Line

[CAT#: S01YF-1123-KX292]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1202	Magic™ Human MAP3K2 in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

MAP3K2

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Cancer Research

Related Diseases

Lung Cancer. Among its related pathways are NGF Pathway and NF-KappaB Family Pathway

Gene ID

10746

UniProt ID

Q9Y2U5

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Humans have an enzyme called mitogen-activated protein kinase kinase 2 (MEKK2/ERK kinase 2), which is encoded by the MAP3K2 gene. This gene codes for a protein that belongs to the family of serine/threonine protein kinases. The MAP kinase signaling pathway's other kinases are preferentially activated by this kinase. It has been demonstrated that this kinase directly phosphorylates and activates IkappaB kinases, contributing to the NF-kappa B signaling cascade. Additionally, it has been discovered that this kinase binds to and activates protein kinase C-related kinase 2, indicating that it may be involved in a controlled signaling pathway. The customized MAP3K2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Gary

This MAP3K2 overexpression cell line is essential for our study. Mar 30 2020

chat Verified Customer

chat Patricia

I choose the MAP3K2 overexpression cell line with luminescent signals. Nov 10 2022

chat Verified Customer

FAQ

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