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    mProX™ Human LGR6 Stable Cell Line

    [CAT#: S01YF-1023-PY318]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

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    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
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    Product Information

    Target Family
    Orphan Family
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;HCT116;SW480
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    Cancer Research;Metabolic Research
    Related Diseases
    Myxedema;Hair Follicle Neoplasm
    Gene ID
    Human:59352
    UniProt ID
    Human:Q9HBX8

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    LGR6, also known as Leucine-rich repeat-containing G-protein coupled receptor 6, has been identified as a marker of stem cells in various tissues, including the skin, hair follicles, and mammary glands. Recent studies have shown that LGR6+ cells have the potential to regenerate tissue and contribute to wound healing processes. Moreover, LGR6 has been implicated in the Wnt signaling pathway, which plays a crucial role in tissue regeneration and cancer progression. The understanding of LGR6's role in these processes can provide insights into therapeutic strategies for tissue repair and cancer treatment.

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    FAQ

    chat Michael (Verified Customer)

    How does LGR6 contribute to wound re-epithelialization? May 10 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    LGR6 marks epidermal stem cells that have a nerve-dependent role in wound re-epithelialization. Diphtheria toxin-mediated ablation of Lgr6 stem cells can delay wound healing, and skin denervation can mimic this effect. Lgr6 epidermal stem cells are primed for injury response and interact with nerves to regulate their fate. May 10 2022

    chat Patricia (Verified Customer)

    What role does Maresin 1 play in relation to LGR6? Aug 18 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Maresin 1 activates the LGR6 receptor, promoting phagocyte immunoresolvent functions. Through an unbiased screening of over 200 GPCRs, MaR1 was identified as a stereoselective activator for human LGR6, which is expressed in phagocytes. Aug 18 2023

    Related Products by Target
    • mProX™ Human LGR6 Stable Cell Line (CAT#: S01YF-1023-PY318)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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