mProX™ Human ITK Stable Cell Line

[CAT#: S01YF-1123-KX270]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Lot Number

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1175	Magic™ Human ITK in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

ITK

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

Jurkat; CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Cardiovascular Research; Reproductive Research; Autoimmune Research

Related Diseases

Lymphoproliferative Syndrome 1 and Agammaglobulinemia, X-Linked. Among its related pathways are Immune response NFAT in immune response and CD28 Signaling in T-Helper Cell

Gene ID

3702

UniProt ID

Q08881

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Kinase tyrosine-protein Interleukin-2-inducible T-cell kinase, or ITK/TSK for short, is a protein that is encoded by the ITK gene in humans. ITK is a kinase that belongs to the TEC family and is highly expressed in T cells. An intracellular tyrosine kinase expressed in T-cells is encoded by this gene. It is believed that the protein contributes to T-cell differentiation and proliferation. For Th2 and Th17 cell growth and effector function, ITK is functionally significant. It was demonstrated that mice deficient in ITK were resistant to asthma. The customized ITK stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Nancy

The ITK KO cell line design is well-optimized, and the provided documentation is comprehensive. Apr 27 2021

chat Verified Customer

chat William

I would recommend this product to anyone who wants to research ITK. May 05 2020

chat Verified Customer

FAQ

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