mProX™ Human IRAK1 Stable Cell Line
[CAT#: S01YF-1123-KX267]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
IRAK1
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
Jurkat; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Autoimmune Research; Infectious Research; Inflammation Research
Related Diseases
Pediatric Systemic Lupus Erythematosus and Mumps. Among its related pathways are MyD88 dependent cascade initiated on endosome and Bacterial infections in CF airways
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Encoded by the IRAK1 gene in humans, interleukin-1 receptor-associated kinase 1 (IRAK-1) is an enzyme. The immune system's ability to eradicate bacteria, viruses, and other pathogens is aided by immune cells like monocytes and macrophages, which express inflammatory genes under the control of IRAK-1. IRAK-1 is a member of the IRAK family, which also includes IRAK-2, IRAK-3, and IRAK-4. During a pathogenic attack, signaling pathways produce inflammatory chemicals that activate IRAK-1. Kinase enzymes, such as IRAK-1, control pathways in the innate and adaptive immune systems. Rheumatoid arthritis is associated with signaling through IRAK-1. Furthermore, IRAK-1 contributes significantly to cancer. The customized IRAK1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Ronald
The human IRAK1 overexpression cell line has become a crucial tool in our lab, helping us gain deeper insights into angiogenesis and related processes.
Sep 26 2020
Verified Customer
Amy
I can confidently say that the IRAK1 cell line is a fantastic tool.
Nov 04 2021
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
