mProX™ Human INSRR Stable Cell Line

[CAT#: S01YF-1123-KX269]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1174	Magic™ Human IRR in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

INSRR

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Ocular Research

Related Diseases

Rickettsialpox and Regular Astigmatism. Among its related pathways are GPCR Pathway and ERK Signaling

Gene ID

3645

UniProt ID

P14616

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

In Pima Indians and Caucasians, the 1q21-q23 area contains the INSRR gene, which codes for the insulin receptor-related receptor (IRR). This region has been linked to type-2 diabetes mellitus. IRR may be important in controlling the mass of β-cells that produce insulin, even if the ligand and biological function of this receptor are still unknown. Its tyrosine kinase phosphorylates proteins implicated in insulin signaling. Defects in INSRR may thereby increase a person's risk of developing type-2 diabetes. The customized INSRR stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Shirley

The mouse INSRR cell line is a good product for general routine use from Creative Biolabs. Oct 11 2021

chat Verified Customer

chat Jennifer

I recently purchased the INSRR overexpression cell line, and it has been a valuable tool in my laboratory work. Jul 23 2022

chat Verified Customer

FAQ

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