mProX™ Human HASPIN Stable Cell Line
[CAT#: S01YF-1123-KX253]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
In eukaryotes, protein kinases are a diverse class of enzymes that are crucial to numerous cellular functions. A number of these proteins are active kinases; one such example is haspin, an unusual eukaryotic protein kinase that lacks sequence homology with other eukaryotic protein kinases and is exclusive to haploid germ cells. During mitosis, the serine/threonine kinase known as haspin binds to chromosomes and phosphorylates histone 3's threonine 3. Defective mitosis arises from overexpression or loss of haspin. Haspin inhibitors have been demonstrated to have strong anti-tumoral effects. Since threonine 3 of histone 3 is the only substrate for Haspin, inhibiting Haspin may not be as harmful as other anticancer drugs. The customized HASPIN stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Linda
Despite its competitive price, the HASPIN cell line exhibited excellent binding affinity and sensitivity comparable to more expensive alternatives.
Feb 23 2021
Verified Customer
Shirley
The HASPIN cell line is a fantastic solution for researchers looking to save money without compromising quality.
Aug 22 2020
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
