mProX™ Human GRK7 Stable Cell Line
[CAT#: S01YF-1123-KX250]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
GRK7
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Ocular Research
Related Diseases
Enhanced S-Cone Syndrome and Oguchi Disease 1. Among its related pathways are Activation of cAMP-Dependent PKA and Visual phototransduction
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Phototransduction is mediated by the serine/threonine-specific protein kinase known as G-protein-coupled receptor kinase 7 (GRK7). During high acuity color vision, this enzyme catalyzes the phosphorylation of cone (color) photopsins in retinal cones, mostly in the fovea. A member of the G protein-coupled receptor kinase family is GRK7. Mammalian retinal cone cells are the primary home of GRK7, where it phosphorylates light-activated photopsins, which are G protein-coupled receptors that detect red, green, and blue light. The capacity of the enzyme to identify color opsins in cone outer segment disk membranes is regulated by the post-translational modification of GRK7 through α-carboxyl methylation and geranylgeranylation. The customized GRK7 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Helen
The GRK7 cell line has proven valuable in various experimental setups, and its compatibility with different techniques makes it a versatile asset for our investigations.
Sep 13 2022
Verified Customer
Michelle
I believe this is a simple, sensitive and effective GRK7 cell line.
Mar 01 2021
Verified Customer
FAQ
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