mProX™ Human FRK Stable Cell Line
[CAT#: S01YF-1123-KX246]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
FRK
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
MDA-MB-231; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Cancer Research
Related Diseases
Co-Trimoxazole Allergy and Liver Benign Neoplasm. Among its related pathways are PIP3 activates AKT signaling and Innate Immune System
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Encoded by the FRK gene in humans, fyn-related kinase (FRK, previously tyrosine protein kinase 5) is an enzyme. The TYR family of protein kinases includes the protein that this gene encodes. This nuclear protein tyrosine kinase may inhibit growth during the G1 and S phases of the cell cycle. Following its initial discovery in 1993, research on FRK suggested that the enzyme may have a tumor-suppressive role. Additional functional analysis of the tyrosine kinase in many cancer types implies that FRK might also be carcinogenic. In particular, knockdown or catalytic inhibition of FRK inhibits key cellular activities in pancreatic and brain malignancies, whereas ectopic expression of FRK decreases cell proliferation and migration in breast and liver cancer. The customized FRK stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Anthony
The affinity is very good and I definitely recommend this FRK cell line.
May 27 2021
Verified Customer
Richard
We are satisfied with this FRK cell line and we will use it in our experimental projects.
Jan 01 2020
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
