mProX™ Human FGFR1 Stable Cell Line
[CAT#: S01YF-1123-KX237]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
FGFR1
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
NSCLC; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Cancer Research
Related Diseases
Osteoglophonic Dysplasia and Encephalocraniocutaneous Lipomatosis. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Fibroblast growth factor receptor 1 (FGFR1) is a receptor tyrosine kinase whose ligands are certain members of the fibroblast growth factor family. It is also referred to as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331. It has been demonstrated that FGFR1 is linked to clonal eosinophilias and Pfeiffer syndrome. Mice that are genetically modified to be devoid of a functional Fgfr1 gene pass away before reaching 10.5 days of gestation. In terms of the musculoskeletal system and the development and organization of tissues derived from mesoderms, embryos show severe defects. The correct development of the limbs, skull, outer, middle, and inner ear, neural tube, tail, and lower spine appears to depend on the Fgfr1 gene for the truncation of embryonic structures and the synthesis of muscle and bone tissues. The customized FGFR1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Helen
A very stable FGFR1 cell line, especially as there has not been much variation change during my use.
Dec 06 2022
Verified Customer
Brian
If you are looking for a good value FGFR1 cell line for drug discovery, this is the one.
May 08 2022
Verified Customer
FAQ
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