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    mProX™ Human FCGR1A Stable Cell Line

    [CAT#: S01YF-1023-PY156]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Fc Receptor Cell Lines

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    Host Cell Type:
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    Product Information

    Target Family
    Fc Receptor
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;SK-OV-3
    Target Classification
    Fc Receptor Cell Lines
    Target Research Area
    Infectious Research
    Related Diseases
    Peritonitis; Pharyngitis
    Gene ID
    Human:2209
    UniProt ID
    Human:P12314

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    FCGR1A, also known as Fc gamma receptor Ia, has been studied in various contexts. In the field of tuberculosis, FCGR1A gene expression has been found to differ significantly between individuals with latent TB infection (LTBI) and active TB (ATB), suggesting its potential as a biomarker for distinguishing between the two conditions. In rheumatoid arthritis, FCGR1A has been identified as a molecular imaging marker for characterizing synovitis, a key feature of the disease. FCGR1A has also been implicated in maintaining sperm fertilization capacity during semen cryopreservation in sheep. Additionally, in the context of hereditary angioedema (HAE), FCGR1A gene expression levels have been found to be associated with disease severity. Finally, in the field of neuroinflammation induced by lead exposure, FCGR1A has been studied in the context of microglia and astroglia activation. Overall, FCGR1A has shown potential in various applications, including as a biomarker, imaging marker, and regulator of cellular function in different disease contexts.

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    FAQ

    chat Peyton Miller (Verified Customer)

    What is the role of FCGR1A in Alzheimer's disease? Jun 25 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    FCGR1A, along with other immune pathway genes, has been identified to associate with Alzheimer's disease through deleterious protein-coding variants. Jun 25 2020

    chat Jordan Miller (Verified Customer)

    Can FCGR1A serve as a biomarker in cancer? Aug 10 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    FCGR1A has been identified as a potential biomarker and is correlated with immune infiltration in various cancer types. Aug 10 2020

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