mProX™ Human EEF2K Stable Cell Line
[CAT#: S01YF-1123-KX222]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
EEF2K
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
HCC; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Cancer Research
Related Diseases
Lung Cancer. Among its related pathways are MTOR signalling and Translation Insulin regulation of translation
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The human enzyme known as eukaryotic elongation factor-2 kinase, or eEF-2K, is encoded by the EEF2K gene. In the calmodulin-mediated signaling pathway, which connects several upstream signals to the control of protein synthesis, eEF-2 kinase is a highly conserved protein kinase. It inhibits the action of eukaryotic elongation factor 2 (EEF2) by phosphorylating it. This kinase's elevated activity is seen in many malignancies, making it a potential target for anti-cancer therapy. The expression of eEF-2K is frequently elevated in cancerous cells, such as those seen in the breast and pancreas, and it facilitates several processes such as cell division, survival, invasion, motility, and migration. Additionally, it has been proposed that eEF-2K, via controlling the production of neuronal proteins, may contribute to the quick antidepressant effects of ketamine. The customized EEF2K stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Karen
The EEF2K cell line has become a crucial tool in our lab, helping us gain deeper insights into angiogenesis and related processes.
Mar 22 2023
Verified Customer
Amanda
As a researcher in vascular biology, I can confidently say that the EEF2K cell line is a fantastic tool. It has significantly improved the accuracy and precision of our experiments.
Mar 08 2023
Verified Customer
FAQ
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