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  • mProX™ Human DYRK4 Stable Cell Line

    [CAT#: S01YF-1123-KX221]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX1108 Magic™ Human DYRK4 in Vitro Assay Human Kinase Assay

    Product Information

    Target Protein
    DYRK4
    Target Family
    Kinases/Enzyme Drug Discovery Assays and Products
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Kinase Cell Lines
    Target Research Area
    Metabolic Research; Reproductive Research
    Related Diseases
    Intellectual Developmental Disorder, Autosomal Dominant 7 and Abdominal Obesity-Metabolic Syndrome 3
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4, or DYRK4, is crucial for the growth, survival, and multiplication of cells. According to Northern Blot research, DYRK4 expression in the testis is highly confined to stage VIII postmeiotic spermatids. A DYRK4 defective mouse line's analysis revealed that DYRK4 is not necessary for male fertility, indicating that some DYRK isoforms have redundant functions during spermiogenesis. The N-terminal half of the DYRK4 protein has a DYRK homology box, which is followed by a central kinase domain with a YxY loop. The customized DYRK4 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Emily

    I recently had the opportunity to try the DYRK4 cell line from Creative Biolabs, and I am quite impressed. The product arrived promptly, and the packaging was secure. Mar 27 2022

    chat Verified Customer

    chat Elizabeth

    I can't speak highly enough about the DYRK4 cell line. It has exceeded my expectations in terms of performance and has become an invaluable asset in our lab. Nov 25 2020

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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