mProX™ Human DYRK2 Stable Cell Line
[CAT#: S01YF-1123-KX219]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
DYRK2
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Reproductive Research
Related Diseases
Intellectual Developmental Disorder, Autosomal Dominant 7. Among its related pathways are Gene expression (Transcription) and Regulation of TP53 Activity
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The DYRK2 gene in humans codes for the enzyme dual-specificity tyrosine-phosphorylation-regulated kinase 2, or more specifically, dual-specificity kinase. As a member of a family of protein kinases, DYRK2 is likely involved in the growth and development of cells. The ability of the family to autophosphorylate on tyrosine residues and the structural similarities of their kinase domains characterize them. In vitro tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B have been demonstrated by DYRK2. DYRK2 has been found to have two isoforms. There is no 5' terminal insert in isoform 1, which is the major isoform. The customized DYRK2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Nancy
The DYRK2 cell line worked as advertised and was a cost-effective alternative in our studies. We obtained consistent results, and the cell line showed good stability over extended periods.
Mar 07 2020
Verified Customer
Jessica
The DYRK2 cell line worked flawlessly, and the detailed protocols provided by the company made the whole process much easier.
Nov 07 2020
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
