mProX™ Human CDK2 Stable Cell Line

[CAT#: S01YF-1123-KX184]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1066	Magic™ Human CDK2/CycA2 in Vitro Assay	Human		Kinase Assay
S01YF-1122-KX1067	Magic™ Human CDK2/CycE1 in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

CDK2

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Cancer Research; Ocular Research

Related Diseases

Breast Cancer and Retinoblastoma. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects

Gene ID

1017

UniProt ID

P24941

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The CDK2 gene in humans codes for the enzyme cyclin-dependent kinase 2, sometimes referred to as cell division protein kinase 2 or Cdk2. The cyclin-dependent kinase family of Ser/Thr protein kinases includes the protein that this gene encodes. This protein kinase shares a great deal of similarities with the S. cerevisiae cdc28 gene products. This protein interacts with and is controlled by the complex's regulatory subunits, which include cyclin A or E. Phosphorylation is another factor that controls its action. This gene has been found to have numerous transcription beginning sites and alternatively spliced variants. It has lately been questioned whether this protein plays a role in the G1-S transition because cells lacking Cdk2 are said to function normally during this phase. The customized CDK2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Melissa

I think this is a quality CDK2 cell line for drug discovery. Nov 05 2022

chat Verified Customer

chat Sharon

Very good CDK2 KO cell line for drug discovery. Feb 19 2023

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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