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  • mProX™ Human CDC7 Stable Cell Line

    [CAT#: S01YF-1123-KX177]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1122-KX1057 Magic™ Human CDC7/ASK in Vitro Assay Human Kinase Assay

    Product Information

    Target Protein
    CDC7
    Target Family
    Kinases/Enzyme Drug Discovery Assays and Products
    Target Protein Species
    Human
    Host Cell Type
    HCC; CHO-K1; HEK293
    Target Classification
    Kinase Cell Lines
    Target Research Area
    Ocular Research
    Related Diseases
    Glaucoma, Primary Open Angle. Among its related pathways are Activation of the pre-replicative complex and Gene expression (Transcription)
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Cell division cycle 7-related protein kinase is an enzyme that in humans is encoded by the CDC7 gene. At the stage of chromosomal DNA replication, the Cdc7 kinase regulates the cell cycle. Since the Cdc7 kinase protein is present in the majority of eukaryotic cells, the gene CDC7 appears to have been conserved throughout the evolution of eukaryotic cells. The protein that this gene codes for is a kinase-active cell division cycle protein that is primarily found in the nucleus. The protein regulates the course of the cell cycle and is necessary for the start of DNA replication. For certain cancers, overexpression of this gene product might be linked to neoplastic transformation. The discovery of additional transcript sizes points to the possibility of alternative splicing. The customized CDC7 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Charles

    This is a very reliable CDC7 KD cell line with high sensitivity and specificity, suitable for experiments such as immunofluorescence microscopy and flow cytometry. May 14 2023

    chat Verified Customer

    chat Emily

    Recommended for all labs based on my experience of using this CDC7 KO cell line. Jun 28 2023

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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