mProX™ Human CDC20 Stable Cell Line
[CAT#: S01YF-1123-KX166]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
CDC20
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
HeLa; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Reproductive Research
Related Diseases
Mosaic Variegated Aneuploidy Syndrome 1 and Mosaic Variegated Aneuploidy Syndrome. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and EML4 and NUDC in mitotic spindle formation
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The CDC20 gene in humans encodes the cell division cycle protein 20 homolog, an important regulator of cell division. To the best of our understanding, its primary role is to trigger the massive 11-13 component complex known as the anaphase promoting complex (APC/C), which is responsible for starting chromatid separation and the anaphase transition.It destroys securin, which eventually leads to the breakdown of cohesin and sister chromatid separation. Additionally, it destroys S and M-phase (S/M) cyclins, inactivating S/M cyclin-dependent kinases (Cdks) and permitting the cell to leave mitosis. At various stages of the cell cycle, CDC20 interacts with numerous other proteins, seemingly serving as a regulatory protein. Two microtubule-dependent activities depend on it: nuclear migration before anaphase, and chromosome separation. The customized CDC20 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Deborah
The CDC20 cell line is easy to work with and consistently provides reliable results.
Jun 28 2023
Verified Customer
Gary
The human CDC20 cell line was easy to use, saving me valuable time in the lab.
Mar 18 2023
Verified Customer
FAQ
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