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  • mProX™ Human CD24 Stable Cell Line

    [CAT#: S01YF-1023-PY226]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    CD Cell Lines

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    Product Information

    Target Family
    CD
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;SKOV3.ip1;Hs 683;SNB-19;A549
    Target Classification
    CD Cell Lines
    Target Research Area
    Cancer Research
    Related Diseases
    Erythroleukemia; Multiple Sclerosis
    Gene ID
    Human:100133941
    UniProt ID
    Human:P25063

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    CD24 is a protein that has been studied in various applications. One study focused on the use of a humanized monoclonal antibody called IMM47 that targets CD24. This antibody showed exceptional anti-tumor efficacy by blocking the CD24/Siglec-10 interaction, making it a potential therapy for cancer immunotherapy. Another study investigated the immunological responses of Arsenicum album 30CH, a homeopathic remedy, as a prophylaxis for COVID-19. CD24 was one of the immunological markers assessed in this study. Additionally, CD24 was identified as one of the genes associated with anoikis in breast cancer, which is important for understanding the prognosis of the disease. Furthermore, CD24 was found to be involved in the CHI3L1/MAF/CTLA4 signaling pathway in triple-negative breast cancer, contributing to immune escape. Lastly, G-quadruplex structures formed by G-rich sequences in the regulatory regions of stem cell markers, including CD24, were characterized and could have implications for gene regulation. Overall, CD24 has been studied in the context of cancer immunotherapy, COVID-19 prophylaxis, breast cancer prognosis, immune escape, and gene regulation.

    Protocols

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    FAQ

    chat Morgan Williams (Verified Customer)

    How does CD24 function in cancer progression? Feb 03 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    CD24 acts as a phagocytic inhibitor in tumor immunity, suppressing macrophage-mediated clearance of cancer cells, and is involved in cancer metastasis and immune evasion. Feb 03 2021

    chat Casey Garcia (Verified Customer)

    Can CD24 be targeted for cancer immunotherapy? Feb 12 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Targeting CD24 with monoclonal antibodies or other therapeutic modalities has shown potential in cancer immunotherapy, particularly in aggressive cancers like large B-cell lymphoma. Feb 12 2023
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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