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    mProX™ Human CCDC6 Stable Cell Line

    [CAT#: S01YF-1023-PY81]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
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    Product Information

    Target Family
    Kinases/Enzyme
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;HCT116
    Target Classification
    Kinase Cell Lines
    Target Research Area
    Cancer Research
    Related Diseases
    Differentiated Thyroid Carcinoma; Papillary Carcinoma
    Gene ID
    Human:8030
    UniProt ID
    Human:Q16204

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    CCDC6 is a gene that is involved in various types of cancer, including thyroid cancer, colorectal carcinoma, sweat gland tumors, and pancreatic ductal adenocarcinoma. In thyroid cancer, CCDC6-RET fusions are associated with concurrent molecular alterations and potentially aggressive features. In colorectal carcinoma, CCDC6 is one of the fusion partners of RET, and RET fusion positive colorectal carcinoma may be a unique molecular subset. In sweat gland tumors, CCDC6-RET fusion transcripts have been identified in cystadenoma/hidrocystoma-like tumors. In pancreatic ductal adenocarcinoma, CCDC6 is one of the genetic alterations observed, along with other common drivers such as KRAS, TP53, and SMAD4. The presence of CCDC6 alterations in these different types of cancer suggests its potential role as a diagnostic and prognostic marker, as well as a potential target for personalized treatment approaches.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human CCDC6 Stable Cell Line (S01YF-1023-PY81). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Skyler Smith (Verified Customer)

    How does CCDC6 affect ovarian carcinoma response to PARP inhibitors? Dec 13 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Disruption of the CCDC6-PP4 axis induces a BRCAness-like phenotype, enhancing sensitivity to PARP inhibitors in high-grade serous ovarian carcinoma. Dec 13 2021

    chat Taylor Williams (Verified Customer)

    Is CCDC6 expression related to prognosis in hepatobiliary carcinoma? Sep 08 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    High expression of CCDC6 is associated with unfavorable outcomes and immune cell infiltration in hepatobiliary carcinoma, suggesting its potential as a predictive biomarker. Sep 08 2021

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    • mProX™ Human CCDC6 Stable Cell Line (CAT#: S01YF-1023-PY81)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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