mProX™ Human CAMKK1 Stable Cell Line
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Protocols
Please visit our protocols page.
Customer Reviews
Michelle
Verified Customer
John
Verified Customer
Any questions about our products? Please visit our frequently asked questions page.
Published Data
Fig.1 CTDSPL and CAMKK1 were identified and validated as targets of miR-181a.
In 293 T cells co-transfected with either pMIR-REPORT construct and miR-181a mimic (or scramble control), dual-luciferase reporter experiments were performed. Three experiments' worth of data were used to calculate the error bars.
Ref: Su, R., et al. "MiR-181 family: regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets." Oncogene 34.25 (2015): 3226-3239.
Pubmed: 25174404
DOI: 10.1038/onc.2014.274
Research Highlights
These findings reveal CAMKK1's new function as an MSC secretome regulator and show that therapeutic benefits can be obtained by directly overexpressing CAMKK1 in infarcted heart tissue.
Dong, Feng, et al. "A novel role for CAMKK1 in the regulation of the mesenchymal stem cell secretome." Stem cells translational medicine 6.9 (2017): 1759-1766.
Pubmed:
28688176
DOI:
10.1002/sctm.17-0046
Using essential elements of the mammalian target of rapamycin/ribosomal protein S6 kinase, 70 kDa, pathway, CaMKK2 acts as a scaffold to assemble CaMKIV and subsequently promote protein synthesis via protein phosphorylation.
Lin, Fumin, et al. "The camKK2/camKIV relay is an essential regulator of hepatic cancer." Hepatology 62.2 (2015): 505-520.
Pubmed:
25847065
DOI:
10.1002/hep.27832
