Human KCNQ2 Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX416]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human KCNQ2 for Protein Expression.
Target Protein
KCNQ2
Target Protein Species
Human
Target Classification
Ion Channel
Target Research Area
Auditory and Otology Research; CNS Research
Related Diseases
Developmental And Epileptic Encephalopathy; Seizures, Benign Familial Neonatal; Benign Familial Neonatal Epilepsy
Target Family
Voltage Gated Potassium Channel
Vector
pME
Vector Type
Mammalian Transient Expression Vector
Note
Resistance
AmpR
Growth Temperature
37°C
Relevant Promoters
CMV, SV40, EF1a, CAG etc.
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
Protein Expression
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Potassium voltage-gated channel subfamily Q member 2
Introduction
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
Alternative Names
EBN; BFNC; DEE7; EBN1; ENB1; HNSPC; KV7.2; KCNA11; potassium voltage-gated channel subfamily KQT member 2; neuroblastoma-specific potassium channel subunit alpha KvLQT2; potassium channel, voltage gated KQT-like subfamily Q, member 2; voltage-gated potassium channel subunit Kv7.2; KCNQ2; Potassium voltage-gated channel subfamily Q member 2
Gene ID
UniProt ID
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