Human CD74 & ROS1 Membrane Protein Retroviral Expression Plasmid
[CAT#: S01YF-1124-KX946]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human CD74 & ROS1 for Retrovirus Production.
Target Protein
CD74; ROS1
Target Protein Species
Human
Target Classification
Kinases/Enzyme
Target Research Area
Inflammation Research
Related Diseases
Nk Cell Deficiency; Chronic Nk-Cell Lymphocytosis
Target Family
Kinases/Enzyme
Vector
pRV
Vector Type
Retroviral Expression Vector
Note
Resistance
AmpR
Growth Temperature
37°C
Relevant Promoters
CMV, SV40, EF1a, CAG etc.
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Fluorescent Markers
EGFP, mCherry etc.
Selection Markers
Puromycin, Hygromycin, Neomycin, Blasticidin etc.
Product Properties
Applications
Retrovirus Production
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
CD74 molecule
Introduction
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Alternative Names
CD74; II; p33; DHLAG; HLADG; Ia-GAMMA; HLA class II histocompatibility antigen gamma chain; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule, major histocompatibility complex, class II invariant chain; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; a-associated invariant chain; MHC HLA-DR gamma chain; gamma chain of class II antigens; CD74 molecule
Gene ID
UniProt ID
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