Human 4-1BB Membrane Protein Lentivirus
[CAT#: S01YF-0624-KX9]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Lentivirus
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order lentivirus expressed human 4-1BB.
Target Protein
4-1BB
Target Classificationp
Immune Checkpoint
Target Family
Immune Checkpoint
Target Protein Species
Human
Protein Tag
Based on specific requirements (Flag, StrepII, His, etc.)
Buffer
HBSS
Titer
≧1.00E+8 TU/mL
Transfer Plasmid Backbone
pCDH or specific requirements
Size
100 µL×10 vials, 1 mL
Fluorescent Markers
EGFP, mCherry etc.
Selection Markers
Puromycin, Hygromycin, Neomycin, Blasticidin etc.
Target Research Area
Cancer Research; Inflammation Research
Related Diseases
Autoimmune Myocarditis; Immunodeficiency
Quality Control
Titer Determination Method
RT-qPCR
Sterility Testing
Negative
Mycoplasma Testing
Negative
Transfection Efficiency
Positive (if EGFP is included in the transfer plasmid)
Endotoxin Level
Based on specific requirements
Product Properties
Application
Stable cell line generation; Protein expression; Biochemical assays
Safety Notes
Since the HIV genes are expressed from packaging plasmids devoid of the packing signal, none of the HIV genes will be expressed in the transduced cells. The pseudotyped lentiviruses need to be used in a Biosafety Level 2 facility even if they are replication-incompetent.
Shipping
Dry ice
Storage
Store at -80°C and avoid repeated freeze-thaw cycles.
Target
Full Name
TNF receptor superfamily member 9
Introduction
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Alternative Names
TNFRSF9; ILA; 4-1BB; CD137; CDw137; tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; CD137 antigen; T cell antigen ILA; T-cell antigen 4-1BB homolog; homolog of mouse 4-1BB; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; receptor protein 4-1BB; TNF receptor superfamily member 9
Gene ID
UniProt ID
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