GHRL
The ghrelin-obestatin preproprotein that is broken into the two peptides ghrelin and obestatin is encoded by this gene. Ghrelin is a potent appetite stimulant and is crucial for maintaining homeostasis in the energy system. It begins to secrete when the stomach is empty, and after it binds to the growth hormone secretagogue receptor in the hypothalamus, growth hormone is secreted (somatotropin). Ghrelin is believed to control a variety of processes, including pancreatic glucose-stimulated insulin production, gastric acid secretion, reward perception via the mesolimbic pathway, and appetite. Obestatin may play many different metabolic roles, including controlling adipocyte activity and glucose metabolism, according to recent studies. Additionally, antisense transcripts for this gene have been found, and these might control the expression of the ghrelin-obestatin preproprotein.
| Full Name | Ghrelin and obestatin prepropeptide |
| Gene ID | Human: 51738 Mouse: 58991 Rat: 59301 Monkey: 574280 |
| UniProt ID | Human: Q9UBU3 Mouse: Q9EQX0 Rat: Q9QYH7 Monkey: A0A5F7ZC09 |
| Alternative Names | MTLRP; appetite-regulating hormone; In2c-preproghrelin; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin preprohormone; ghrelin/obestatin prepropeptide; growth hormone-releasing peptide; motilin-related peptide; prepro-appetite regulatory hormone; preproghrelin |
Product List
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- Product Category:
- Membranes
- Target Protein: GRLN Target Family: Ghrelin Target Protein Species: Human Host Cell Type: Chem-1 Application: GTPγS Assay; Ligand Binding Assay
- Product Category:
- Membranes
- Target Protein: Ghrelin Target Family: Ghrelin Target Protein Species: Human Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GHRL Target Family: Ghrelin Family Target Protein Species: Rat Host Cell Type: AR42J;CHO-K1;HEK293 Assay Types: Biological assays
